San Francisco 49ers 1968 Season Schedule & Scores
| Overall record: | N/A |
| Home record: | |
| Away record: |
| Away | Home | Date | Result | ||
|---|---|---|---|---|---|
 SF | @ |  BAL | Sun, Sep 15th, 1968 | L10-27 | |
 STL | @ | SF | Sun, Sep 22nd, 1968 | L17-35 | |
 ATL | @ | SF | Sun, Sep 29th, 1968 | L13-28 | |
| SF | @ |  LA | Sun, Oct 6th, 1968 | L10-24 | |
| BAL | @ | SF | Sun, Oct 13th, 1968 | W42-14 | |
| SF | @ |  NYG | Sun, Oct 20th, 1968 | W26-10 | |
| SF | @ |  DET | Sun, Oct 27th, 1968 | W14-7 | |
 CLE | @ | SF | Sun, Nov 3rd, 1968 | W33-21 | |
| SF | @ |  CHI | Sun, Nov 10th, 1968 | L19-27 | |
| LAR | @ | SF | Sun, Nov 17th, 1968 | T20-20 | |
| SF | @ |  PIT | Sun, Nov 24th, 1968 | W45-28 | |
 GB | @ | SF | Sun, Dec 1st, 1968 | L20-27 | |
 MIN | @ | SF | Sun, Dec 8th, 1968 | W30-20 | |
| SF | @ | ATL | Sun, Dec 15th, 1968 | W14-12 |
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